ConXus Profile v2.5

Available: November 1, 2009

ConXus Profile v2.5 has been developed to provide compliance with GINA regulations that come into effect on December 6th through removal of any questions relating to family medical history. The removal of these questions requires modifications to many of the future disease risk algorithms used in the instrument.

This release also includes minor changes to the collection and assessment of data regarding smoking and physical activity, and the addition of questions regarding hearing and vision impairment, to provide compliance with the 2009 NCQA Wellness and Health Promotion technical specifications.

ConXus Profile v2.5 includes changes to the following product components:

  • Questionnaire
  • Member report
  • Provider report
  • Data export file
  • Data elements available through member data Web Services

Upgrade Timeline and Process

ConXus Profile v2.5.0 (English and Spanish) is available for upgrade from November 1, 2009. Please contact PDHI Client Services to request detailed technical documentation and to schedule your upgrade.

Description of Enhancements

The changes included in version 2.5 are as follows:

GINA Compliances

The following changes are included to provide compliance with GINA:

  • Removal of any questions related to family history from the questionnaire.
  • Modification of assessment algorithms for future disease risk to exclude family history information. The assessments impacted are:
    • Breast cancer
    • Colorectal cancer
    • Depression
    • Diabetes
    • Heart disease
    • Hypertension
  • Update of the member report future disease risk sections to describe the increased risk that may result from family history.

The removal of family history questions and resulting changes to the future disease risk algorithms give a small shift towards lower risk across a population, and a slight reduction in the number of HRAs assessed as “Incomplete” as a result of missing values or “Don’t know” responses.

Most HRAs that change risk group move one level, i.e. from high risk to moderate risk, or from moderate risk to low risk. The exception is diabetes risk, where 3% of the HRAs move from high risk to low risk, representing a subset of the population age 44 to 56 years with waist circumference less than 38.4 inches.

An analysis of these changes in risk categorization, based on 35,000 HRAs within the ConXus database, is shown in the table below.

Population Stratification Changes – pre-GINA to post-GINA
Breast cancer risk Diabetes risk
Low 4.1% Low 5.9%
Moderate -1.1% Moderate 0.8%
High -1.0% High -3.8%
Incomplete -1.9% Incomplete -2.9%
Colorectal cancer risk Heart disease risk
Low  7.4% Low  1.6%
Moderate -1.4% Moderate -1.0%
High -0.4% High  0.0%
Incomplete -5.6% Incomplete -0.5%
Depression risk Hypertension risk
Low  4.0% Low  7.9%
Moderate -1.1% Moderate -2.1%
High -2.9% High -4.6%
Incomplete  0.0% Incomplete -1.3%

2009 NCQA Wellness and Health Promotion Technical Specifications

The following changes are included to provide compliance with NCQA WHP technical specifications:

  • Modification of questions regarding smoking history.
  • Modification of the questions regarding physical activity and the assessment algorithm to determine physical activity risk.
  • Addition of questions for hearing impairment and vision impairment.


A question requesting preferred email address has been added to the Contact Information section to facilitate email delivery of reminders, appointments and other communications that do not contain personal health information (PHI).